OvaBoost Supports Healthy Ovulation and Egg Quality in Healthy Women Who Are Trying To Conceive
OvaBoost is a dietary supplement that contains a combination of vitamins and antioxidants including myo-inositol, folate, melatonin, coenzyme Q10, vitamin E, grapeseed extract and alpha-lipoic acid to support egg health and ovulation.
Tell Me More About OvaBoost
OvaBoost has a unique formulation highlighted by a trio of ingredients – Myo-inositol, folic acid (also called folate), and melatonin – that has been studied as a way to support egg quality in women undergoing IVF. Folic acid is already well-known for its ability to prevent neural tube defects, and it is recommended that all women of child-bearing age take in a sufficient amount of folic acid. But, recent research in women undergoing IVF treatments indicates that when folic acid is given in combination with two powerful antioxidants, myo-inositol and melatonin, egg quality is significantly improved. (See a list of related scientific articles below.)
In addition, OvaBoost includes Coenzyme Q10 (CoQ10), which is an antioxidant. But, CoQ10 also plays an important role in energy production within egg cells. Once conception occurs, the amount of cell division that occurs to allow the egg to grow into an embryo and successfully implant into the wall of the uterus requires a tremendous amount of energy. CoQ10 works within the mitochondria (the energy powerhouse of the cell) of the egg cell to help ensure that energy production is optimal.
Finally, OvaBoost contains three additional antioxidant ingredients, Vitamin E, grapeseed extract and alpha-lipoic acid, to help ensure your egg cells are adequately protected from the damaging effects of free radicals.
The formulation for OvaBoost was developed on the basis of a large, and ever-growing, body of scientific literature that suggests how egg quality can be maintained as we age, and which points to effective and promising natural ingredients for supporting egg quality and healthy ovarian function. See Supporting Research below for a sample of the scientific papers (all available in MEDLINE) that were reviewed and considered in the development of this product.
Folate vs Synthetic Folic Acid
Due to the fundamental role that folic acid plays in reproductive health and pregnancy wellness, further explanation about this crucial vitamin is warranted. The words folate and folic acid are often used interchangeably to describe the vitamin known as vitamin B9. Folate is the form of this vitamin that naturally occurs in foods – dark, green leafy vegetables are good sources of naturally occurring folate. Folic acid is the synthetic form of vitamin B9 that is found in fortified foods and most dietary supplements. While the research in this area is still emerging, many experts believe that folic acid is not sufficiently metabolized by some people. To help ensure optimal utilization of the folate in OvaBoost, OvaBoost features methyl folate, a more bioavailable form of folate than synthetic folic acid. Get the best bang for your buck when it comes to supplementing with this important vitamin!
Frequently Asked Questions
How much Myo-Inositol does OvaBoost contain?
OvaBoost provides 2 grams of Myo-inositol per daily dosage.
Who should take OvaBoost?
OvaBoost is intended to support egg quality and enhance the process of ovulation in healthy women who are trying to conceive women.
How long should I take OvaBoost?
We recommend taking OvaBoost for a minimum of 3 months, or as long as you are actively trying to conceive. OvaBoost can be discontinued once pregnancy has been confirmed.
Are there any known side effects or contraindications?
OvaBoost has no known side effects. However, as with any dietary supplement, if you have a pre-existing medical condition, we recommend that you discuss taking OvaBoost with your doctor. Please consult with your physician before taking OvaBoost if you have been prescribed a medication for depression or anxiety, or if you are taking the herb St. John’s Wort, as large amounts of Myo-inositol may have additive effects when taken along with drugs and herbs classified as selective serotonin reuptake inhibitors (SSRI) and selective serotonin-norepinephrine reuptake inhibitors (SNRI).
I notice that OvaBoost contains melatonin. Will this product impact my typical sleep pattern?
Melatonin is a powerful antioxidant compound that has been shown to be helpful for supporting egg quality, especially when given in combination with folic acid and Myo-inositol. In addition, melatonin is a frequently recommended natural ingredient for helping to restore normal sleep cycles in people with insomnia. OvaBoost contains a small amount of melatonin, similar to the amount given to trying-to-conceive women in clinical trials looking at the benefits of this natural ingredient for improving egg quality. When taken in the recommended dosage, we do not expect OvaBoost to impact your sleep cycle, or your day time energy levels or alertness. If you experience a change, we do recommend that you take all capsules just before bedtime.
Note: The specific combination of ingredients in OvaBoost has not been scientifically studied. The list of studies below represents a sample of the available literature on individual ingredients in OvaBoost.
Comparison of (6S)-5-methyl-tetrahydro folic acid v. folic acid as the reference folate in longer-term dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults. Wright AJ., King MJ., Wolfe CA., Powers HJ., Finglas PM. Br J Nutr. 2010 Mar; 103(5): 724-9.
Crossover comparative bioavailability study of 5-methyltetrahydrofolate glucosamine salt (GN10G) compared to the reference Metafolin in healthy volunteers. Ismaili, Shefqet. Final Report IPAS-5MTHFA-583-09.
Effect of the treatment with Myo-inositol plus folic acid plus melatonin in comparison with a treatment with Myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial. Rizzo P, et al. Eur Rev Med Pharmacol Sci. 2010 Jun; 14(6): 555-61.
The efficacy of melatonin administration on oocyte quality. Batioglu AS, et al. Gynecol Endocrinol. 2012 Feb; 28(2); 91-3
The role of melatonin as an antioxidant in the follicle. Tamura H, et al. Journal of Ovarian Research 2012, 5:5.
Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial. Unfer V et al. Eur Rev Med Pharmacol Sci. 2011 Apr;15(4):452-7.
Effects of myo-inositol supplementation on oocyte’s quality in PCOS patients: a double-blind trial. Ciotta L, et al. Eur Rev Med Pharmacol Sci. 2011 May;15(5):509-14.
Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances but does not improve the sleeping problems. Eryilmaz OG et al. J Assist Reprod Genet – 01-SEP-2011; 28(9): 815-20
Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. Tamura H, et al. J Pineal Res 2008; 44(3): 280-7
Effect of supplementation with Myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study. Unfer V, et al. Gynecol Endocrinol. 2011 Nov;27(11):857-61.
Contribution of Myo-inositol and melatonin to human reproduction. Carlomagno G, et al. Eur J Obstet Gynecol Reprod Biol.2011 Dec;159(2):267-72.
Inositol administration reduces oxidative stress in erythrocytes of patients with polycystic ovary syndrome. Don G, et al. Eur J Endocrinol. 2012 Apr;166(4):703-10.
Antioxidants to enhance fertility: role of eNOS and potential benefits. Visioli F, Hagen TM. Pharmacol Res.2011 Nov;64(5):431-7.
Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading. Turi A, et al. Arch Gynecol Obstet. 2012 Apr;285(4):1173-6.
The effects of oxidative stress on female reproduction: a review. Agarwal A, et al. Reprod Biol Endocrinol. 2012 June 29; 10(1): 49.
Age-related changes in mitochondrial function and new approaches to study redox regulation in mammalian oocytes in response to age or maturation conditions. Eichenlaub-Ritter U, et al. Mitochondrion. 2011 Sep;11(5):783-96.
FORMULATED IN THE USA in our FDA compliant facility that adheres to Good Manufacturing Practices (GMP).
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